Ovulation Induction is one of most successful fertility treatmentsused to overcome infertility and assist in various infertility treatment options such as In Vitro Fertilization (IVF) and Intrauterine Insemination (IUI) procedures. Most of us have only heard about it, here are some details that you need to know about Ovulation Induction.
Ovulation Induction (OI) is a stimulation process. It is a fertility treatment which includes the usage of various medications so as to enhance the number of eggs produced during a cycle or control or cause ovulation.
This technique is applied so that sexual intercourse, In Vitro Fertilization (IVF) and Intrauterine Insemination (IUI) methods can be programmed at an optimal time and the possibility of pregnancy can be improved.
Before and during the In-Vitro Fertilization process, the fertility expert monitorsthe patient's ovaries and the timesthe egg release. The OI treatment helps in timely egg retrieval and increases the chances of success of IVF procedure.
Who could benefit from OI Treatment?
Ovulation Induction Treatment is beneficial for women:-
With unexplained infertilityWith extended, irregular or abnormal cyclesWho are not ovulatingWith no male factor infertilityWith PCOS, who do not ovulate on their own regularly, and want to get pregnant
Conditions under which Ovulation Induction Treatment may fail
women with over 36 years of agewomen with tubal blockage or critical tubal damagefemale with severe endometriosiswith other possible Complications
Steps involved in Ovulation Induction Treatment- also part of IVF Process
Steps involved are as follows:-
Step 1 – Stimulation
Ovulation induction includes drugs clomiphene citrate, gonadotropins, etc. These oral drugs support the growth of the follicles carrying the eggs.These medicines act in place of FSH (follicle-stimulating hormone), and then the ovaries produce multiple follicles and mature, high-quality eggs.The hormone levels and follicular maturation are tracked throughout the stimulation cycle and subsequently medication protocol is set for best results.
Step 2- Control
Blood tests and ultrasound are done to monitor the influence of the hormonal medicines introduced.It helps to analyse the hormone levels, identify the maturation status of eggs, and assess the size of follicles.The process is known as Follicular Monitoring.
Step 3- Egg Release (Ovulation)
When the follicles are set, generally between 16 and 20 millimeters in diameter depending on your medication, an injection of hCG is administered to prepare you for IVF, Intrauterine Insemination (IUI).
Fertility Medicines for OI
Different types of fertility medications are possible for OI.The five types of ovulation drug therapy are discussed here:-
Clomiphene Citrate (Clomid or Serophene):-
This medication is recommended for females with prolonged ovulation cycles and irregular periods; it limits the influences of estrogen and induces the body to generate more follicle-stimulating hormone.
Human Menopausal Gonadotropin (HMG):-
It helps in stimulating the growth of many eggs and follicles during an ovulation cycle.
It is obtained from the urine of postmenopausal females.
Follicle-Stimulating Hormone (FSH):-
It is used to stimulate the maturation of the follicles (fluid-filled sacks) which carry the eggs.
Human Chorionic Gonadotropin (hCG):-
It is used to induce ovulation.
It is produced by the placenta throughout pregnancy and taken from the urine of pregnant females.
Factors that may affect Success rates ofOI
Success rates for induction of ovulation vary considerably and depend on the age of the woman, the type of medicine used, whether there are other infertility circumstances present in the couple, and other factors.Success rate increases after combining it with Intrauterine Insemination (IUI) and In Vitro Fertilization (IVF).